Potential of <i>Allium sativum</i> in blood pressure control involves signaling pathways: A narrative review

The use of food products and functional foods to manage treat several health conditions is expanding globally. Garlic (Allium sativum) consumption commonly used for its potential therapeutic functions in numerous cardiometabolic disorders, including hypertension. proposed blood pressure–reducing effects garlic after influence metabolic pathways, resulting potentially beneficial outcomes. first postulated mechanism nitric oxide (NO) activation, leading vasodilation. Furthermore, was also shown promote vasodilation by suppressing the renin–angiotensin–aldosterone system (RAAS) formation prostaglandins, angiotensin-converting enzyme activity. garlic-related related high sulfur-containing content associated with forming hydrogen sulfides (H2S). H2S binds activates vascular ATP-sensitive potassium channels (kATP), hyperpolarization, which induces This review summarizes garlic's features mechanical paths that could contribute pressure control.